Connect Sign In
Drug Detection Panel, Umbilical Cord Tissue, Qualitative
Ordering Recommendation
Use to detect and document fetal drug exposure during approximately the last trimester of a full-term pregnancy. For panel testing that includes THC metabolite, refer to Drug Detection Panel and THC Metabolite, Umbilical Cord Tissue, Qualitative (3006371).
New York DOH Approval Status
Specimen Required
Umbilical cord (At least 8 inches, approximately the width of a sheet of paper.)
Drain and discard any blood. Rinse the exterior of the cord segment with normal saline or water. Pat the cord dry and transport at least 8 inches of umbilical cord in a routine urine collection cup or Security Kit for Meconium/Umbilical Drug Detection (ARUP supply #51548) available online through eSupply using ARUP Connect™ or by contacting ARUP Client Services at 800-522-2787.
Refrigerated.
Cords soaking in blood or other fluid. Formalin fixed. Tissue that is obviously decomposed.
Ambient: 1 week; Refrigerated: 3 weeks; Frozen: 1 year
Methodology
Qualitative Liquid Chromatography-Tandem Mass Spectrometry
Performed
Sun-Sat
Reported
1-3 days
Reference Interval
Effective February 20, 2018
| Drugs covered and range of cutoff concentrations. |
|||
|---|---|---|---|
| Drugs/Drug Classes |
Cutoff Concentrations (ng/g) |
Drugs/Drug Classes |
Cutoff Concentrations (ng/g) |
| Buprenorphine | 1 | Amphetamine | 5 |
| Norbuprenorphine | 0.5 | Benzoylecgonine | 1 |
| m-OH-Benzoylecgonine | 1 | ||
| Codeine | 0.5 | Cocaethylene | 1 |
| Dihydrocodeine | 1 | Cocaine | 1 |
| Fentanyl | 0.5 | MDMA (Ecstasy) | 5 |
| Hydrocodone | 0.5 | Methamphetamine | 5 |
| Norhydrocodone | 1 | Phentermine | 8 |
| Hydromorphone | 0.5 | Alprazolam | 0.5 |
| Meperidine | 2 | Alpha-OH-Alprazolam | 0.5 |
| Methadone | 2 | Butalbital | 25 |
| Methadone metabolite | 1 | Clonazepam | 1 |
| 6-Acetylmorphine | 1 | 7-Aminoclonazepam | 1 |
| Morphine | 0.5 | Diazepam | 1 |
| Naloxone | 1 | Lorazepam | 5 |
| Oxycodone | 0.5 | Midazolam | 1 |
| Noroxycodone | 1 | Alpha-OH-Midazolam | 2 |
| Oxymorphone | 0.5 | Nordiazepam | 1 |
| Noroxymorphone | 0.5 | Oxazepam | 2 |
| Propoxyphene | 1 | Phenobarbital | 75 |
| Tapentadol | 2 | Temazepam | 1 |
| Tramadol | 2 | Zolpidem | 0.5 |
| N-desmethyltramadol | 2 | Phencyclidine (PCP) | 1 |
| O-desmethyltramadol | 2 | Gabapentin | 10 |
Interpretive Data
Methodology: Qualitative Liquid Chromatography/Tandem Mass Spectrometry
Detection of drugs in umbilical cord tissue is intended to reflect maternal drug use during approximately the last trimester of a full-term pregnancy. The pattern and frequency of drug(s) used by the mother cannot be determined by this test. A negative result does not exclude the possibility that a mother used drugs during pregnancy. Detection of drugs in umbilical cord tissue depends on extent of maternal drug use, as well as drug stability, unique characteristics of drug deposition in umbilical cord tissue, and the performance of the analytical method. Drugs administered during labor and delivery may be detected. Detection of drugs in umbilical cord tissue does not insinuate impairment and may not affect outcomes for the infant. Interpretive questions should be directed to the laboratory.
For medical purposes only; not valid for forensic use.
Laboratory Developed Test (LDT)
Note
Absolute Minimum: 6 inches. For marijuana metabolite, order Marijuana Metabolite, Umbilical Cord Tissue, Qualitative (ARUP test code 3000256). For alcohol metabolite, order Ethyl Glucuronide, Umbilical Cord Tissue, Qualitative (ARUP test code 3000443).
For kratom analyte, order Kratom, Umbilical Cord, Qualitative (ARUP test code 3005874).
When ordering multipleumbilical cord tests, unless ARUP is otherwise notified, testing will be performed in the following order of priority:
Drug Detection Panel (1.0g)
Marijuana Metabolite (1.0g)
Ethyl Glucuronide (1.0g)
Kratom(1.0 g)
Hotline History
Hotline History
CPT Codes
80346; 80348; 80353; 80361; 80356; 80365; 80373; 80354; 80362; 80355; 80359; 80325; 80345; 80372; 80358; 83992; 80368; 80367 (Alt code: G0482)
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2006622 | Drug Detection Panel, Umbilical Cord | 62364-5 |
| 2006626 | Buprenorphine, Cord, Qual | 82373-2 |
| 2006628 | Codeine, Cord, Qual | 40626-4 |
| 2006629 | Dihydrocodeine, Cord, Qual | 97242-2 |
| 2006630 | Fentanyl, Cord, Qual | 61042-8 |
| 2006631 | Hydrocodone, Cord, Qual | 32080-4 |
| 2006632 | Hydromorphone, Cord, Qual | 32081-2 |
| 2006633 | Meperidine, Cord, Qual | 32088-7 |
| 2006634 | Methadone, Cord, Qual | 32093-7 |
| 2006635 | Methadone Metabolite, Cord, Qual | 41859-0 |
| 2006636 | 6-Acetylmorphine, Cord, Qual | 32099-4 |
| 2006637 | Morphine, Cord, Qual | 32100-0 |
| 2006638 | Naloxone, Cord, Qual | 100357-3 |
| 2006640 | Oxycodone, Cord, Qual | 32101-8 |
| 2006641 | Oxymorphone, Cord, Qual | 91053-9 |
| 2006642 | Propoxyphene, Cord, Qual | 43811-9 |
| 2006644 | Tapentadol, Cord, Qual | 59355-8 |
| 2006645 | Tramadol, Cord, Qual | 97306-5 |
| 2006646 | N-desmethyltramadol, Cord, Qual | 97306-5 |
| 2006647 | O-desmethyltramadol, Cord, Qual | 97292-7 |
| 2006648 | Amphetamine, Cord, Qual | 29530-3 |
| 2006649 | Benzoylecgonine, Cord, Qual | 40609-0 |
| 2006650 | m-OH-Benzoylecgonine, Cord, Qual | 43230-2 |
| 2006652 | Cocaethylene, Cord, Qual | 48946-8 |
| 2006653 | Cocaine, Cord, Qual | 40625-6 |
| 2006654 | MDMA- Ecstasy, Cord, Qual | 40481-4 |
| 2006657 | Methamphetamine, Cord, Qual | 40381-6 |
| 2006658 | Phentermine, Cord, Qual | 100358-1 |
| 2006659 | Alprazolam, Cord, Qual | 61038-6 |
| 2006660 | Alpha-OH-Alprazolam, Cord, Qual | 61037-8 |
| 2006662 | Butalbital, Cord, Qual | 32057-2 |
| 2006663 | Clonazepam, Cord, Qual | 61039-4 |
| 2006664 | 7-Aminoclonazepam, Cord, Qual | 61031-1 |
| 2006665 | Diazepam, Cord, Qual | 61074-1 |
| 2006671 | Lorazepam, Cord, Qual | 61044-4 |
| 2006672 | Midazolam, Cord, Qual | 59712-0 |
| 2006673 | Alpha-OH-Midazolam, Cord, Qual | 97278-6 |
| 2006675 | Nordiazepam, Cord, Qual | 61051-9 |
| 2006676 | Oxazepam, Cord, Qual | 61055-0 |
| 2006677 | Phenobarbital, Cord, Qual | 32108-3 |
| 2006679 | Temazepam, Cord, Qual | 61061-8 |
| 2006682 | Zolpidem, Cord, Qual | 97310-7 |
| 2006683 | Phencyclidine- PCP, Cord, Qual | 32107-5 |
| 2009199 | EER Drug Detection Pan, Umbilical Cord | 11526-1 |
| 2013103 | Norbuprenorphine, Cord, Qual | 82375-7 |
| 2013104 | Norhydrocodone, Cord, Qual | 97286-9 |
| 2013105 | Noroxycodone, Cord, Qual | 97290-1 |
| 2013106 | Noroxymorphone, Cord, Qual | 97296-8 |
| 3001452 | Gabapentin, Cord, Qual | 93121-2 |
Aliases
- Drug Screen, Targeted, Serum or Plasma
- Drugs of Abuse Panel, Meconium - Screen with Reflex to Confirmation/Quantitation
